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KMID : 0061119830110000179
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Bulletin of the Clinical Research Institute
1983 Volume.11 No. 0 p.179 ~ p.179
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Succinylcholine Effect on Low concentration of Halothane and Enflurane Anesthesia during Cesarean Section
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Kwon, Ou-Kyoung
Han, Young-Moon/Chon, Se-Ung
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Abstract
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The effects of halothane and ethrane, in their low concentration, on the depolarizing neuromuscular block were studied in 40 healthy women undergoing elective cesarean section. The patient were divided randomly into two group halothane group (group A) and ethrane group (group B). Ulnar nerve was stimulated using a peripheral nerve stimulator with supra-maximal single switch impulses of 0.2 ms duration at a rate of 1.0 ㎐ and responses of adduction of thumb were measured with a force displacement transducer and recorded with a biophysiography. In group A; 0.5% halothane and, in group B; 1% ethrane were administered.
The results were as follows. The time from intravenous succinylcholine to onset of paralysis was 15.5±3.21 sec in halothane group, and 14.8±3.17 sec in ethrane group. The time from onset of paralysis to full paralysis was 42.2±5.98 sec in halothane group, and 47.1±13.55 sec in ethrane group. Duration of full paralysis was 283.9±68.02 sec in halothane group and 270.8±44.49 sec in ethrane group. Recovery index (T_(25)-T_(75)) was 68.4±16.11 sec in halothane group and 75.4±21.93 sec in ethrane group.
The authors conclude that there is no significant difference between the effects of halothane and ethrane, in their low concentration, on the neuromuscular blocking action of succinylcholine in healthy pregnant women.
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